Last year’s quarter-finalist Danielle Collins advanced by beating Chinese qualifier Wang Xiyu 6-2 4-6 6-4 in the American’s first match since March, when she stepped away from the tour to have endometriosis surgery.
Endometriosis is a condition where tissue that usually covers the inside of the uterus grows outside of it.
“It certainly presented its challenges, but it’s been really kind of shocking, like since surgery I’ve just felt so much better,” the 27-year-old said.
Meanwhile, Victoria Azarenka won the first-round battle between Grand Slam champions, overcoming 2009 winner Svetlana Kuznetsova of Russia 6-4 2-6 6-3 under the Court Philippe Chatrier roof.
Fellow Belarusian and third seed Aryna Sabalenka also advanced with a 6-4 6-3 win over Croatian qualifier Ana Konjuh.
Sabalenka, 23, has been on form on the quicker clay of Stuttgart, where she reached the final, and she also won the Madrid title.