Swansea-based Stephanie Millward swam the second fastest time in the S9 400m freestyle heats and equalled that performance to take silver in the final.
In the men’s 100m backstroke S8, Sutton-in-Ashfield’s Oliver Hynd took bronze ahead of Lancaster’s Thomas Young by 0.56 seconds.
Stockport’s Matthew Walker won his 12th medal in four Paralympics as he took bronze in the men’s 50m freestyle S7.
Chertsey’s Hannah Russell set the leading time in qualifying but finished a distant sixth in the final of the women’s 100m freestyle as Russia’s Oxana Savchenko won gold in a world record beating time of 58.41 seconds.
David Devine got Great Britain’s night in the athletics off to a medal winning start with a bronze in the T13 men’s 1500m final.
The Liverpool-born runner put in a fantastic performance to finish behind Zhiou Abderrahim of Tunisia, who won with a world record three minutes 48.31 seconds, and Kenya’s David Korir who attained the silver.
His achievement was bettered by Dorchester’s Paul Blake in the men’s 400m T36 final as he held on in the final straight to take silver behind Russia’s Evgenii Shvetcov, who broke the world record with a time of 53.31 seconds.